A follow-up sequence keeps sending until something tells it to stop. Each campaign decides what counts as that signal: a reply, a click, an open, a colleague at the same company replying, a reply that confirms a meeting, or a reply that sounds interested. The same block also decides what happens when a reply asks to be removed and what happens when a reply is an automatic away message. Every setting is per campaign, so a nurture sequence and a one-question outreach campaign can behave differently.

1. Open the campaign draft and go to the Sequence step.
2. Switch follow-ups on. The block headed Stop follow-ups when… appears under the stages.
3. Check the conditions that should end the sequence for a recipient.
4. Set the two reply-handling controls underneath the checkboxes.
5. Save the draft. The settings apply from the moment the campaign sends.

Multi-stage follow-ups themselves are available on the Business plan and above. These stop settings sit inside that step, so they appear once follow-ups are available to you.

A new campaign starts with Someone replies already checked, because a reply is the signal almost every sender wants. Everything else is an explicit choice.

Someone at the same company replies is the immediate version. When one person at a company domain replies, everyone else at that domain drops out of the remaining stages right away. Personal email domains are never grouped, so two contacts on the same consumer mail provider are treated as unrelated people.

Higher up the Sequence step there is an older checkbox, Stop follow-ups when anyone from a company replies, with the helper line “If someone from @example.com replies, skip follow-ups for all recipients at that domain”. It is on by default and it does the same job at send time: each pending follow-up is checked against the company before it goes out. Turning the new row on switches on the domain-reply tracking that both of them rely on, so you do not need to change the older checkbox. Leave it as it is.

The dropdown offers four choices:

• Workspace default follows the setting for your workspace. The option names the mode it currently resolves to, and the line under the dropdown spells out what this campaign will therefore do.
• Ask me before removing them sends you a notification titled Unsubscribe request detected. Nothing is suppressed until you confirm it.
• Remove them right away records the opt-out itself and stops that recipient, then tells you with a notification titled Unsubscribed automatically after reply. That one is in-app only, with no email.
• Only flag it on the recipient records the intent on the send and does nothing else.

Removing someone adds them to your opt-out list, which every future send checks, so it reaches beyond this campaign. On the campaign page, a flagged recipient shows a Confirm unsubscribe button in their row until you act on it, and reads Unsubscribed afterwards.

An automatic out-of-office reply is deliberately not treated as a reply. Instead of ending the sequence, it pushes the recipient’s pending follow-ups back by the number of days you set, so the next stage lands after they are back rather than while they are away. The rescheduled send still respects the campaign’s sending days and each stage’s own send time and timezone. Set any whole number of days from 1 to 30; the field starts at 7.

Tell me about interested replies is separate from the two stop conditions above it. It controls the notification you get when a reply reads as interested or confirms a meeting, and it is on unless you turn it off, including on campaigns created before these settings existed. You can leave the two stop conditions off and still be told about the replies worth your attention.

Unsubscribes and bounces always stop follow-ups, whatever you choose here. That line is printed at the bottom of the block for the same reason it is written here: those two are compliance and deliverability behavior, not preferences.

A campaign created before these settings shipped has every condition switched off, so it behaves exactly as it did before. Each condition is an explicit opt-in; nothing was armed on your behalf. You can also stop a single recipient by hand at any time: open the campaign, find them in the recipients table, and use Stop follow-ups. A recipient whose sequence has ended reads Follow-ups stopped in that column.

• Stopping a recipient cancels their remaining follow-up stages only. Everything already sent, and all of its tracking, stays on the campaign.
• Every condition except the company one acts on that recipient alone.
• The settings are edited on a draft, along with the rest of the campaign.
• The block only appears while follow-ups are switched on, because there is nothing to stop without them.